Das Experten SYMBIOS is a revolutionary “living” toothpaste formulated with Bacillus coagulans JYBC-016 — a spore-forming probiotic clinically proven to combat oral pathogens and restore microbiome balance. Designed as the first oral-care paste with targeted probiotic modulation, it reduces S. mutans, controls bad breath, and reinforces local immune defense—making your mouth not just clean, but biologically defended.

Probiotic Engine & Microbial Control

Bacillus coagulans JYBC-016 (40 Billion CFU)
This robust probiotic strain survives harsh oral environments and activates on contact with saliva. It binds to oral surfaces, competes with and inhibits pathogens like Streptococcus mutans and Porphyromonas gingivalis, reducing their virulence without eradicating beneficial flora.

💥 In a 14-day clinical trial, B. coagulans reduced S. mutans in saliva by over 60%, correlating with decreased plaque and caries risk.

Microbiome Harmony Strategy
Rather than killing all microbes (like triclosan), SYMBIOS shifts the oral ecosystem to favor commensals like S. sanguinis. This prevents microbial rebound and protects against dysbiosis and thrush, especially in users overusing antiseptic rinses.

Immunological & Systemic Impact

Immune Modulation Benefits
B. coagulans has shown to boost T-cell responses and increase production of cytokines like IFN-γ and TNF-α during viral exposures (e.g., influenza, adenovirus). In human studies, this led to up to 709% increase in immune signaling molecules, suggesting enhanced readiness against respiratory infections.

💡 Did you know? Unlike lactobacilli, B. coagulans leaves the body within 7 days and does not alter your core microbiome, making it safe for daily long-term use—even in children.

SYMBIOS “LIVING” TOOTHPASTE WITH PROBIOTICS AND PREBIOTICS

Name: SYMBIOS “LIVING” TOOTHPASTE WITH PROBIOTICS AND PREBIOTICS
SKU: DE206

SKU: DE206

14,50 €

70 Mililitro

Cantidad

Key actives: Bacillus coagulans (4 x 10¹⁰ CFU/tube), xylitol, silica, menthol, pyrophosphate

Surfactant: SL30 (SLS alternative — mild, non-irritating)

Safe if swallowed — suitable for children and individuals avoiding fluoride

Eco-friendly rinse-off profile: no endocrine disruptors, no environmental persistence
Xylitol + Menthol + Probiotic synergy eliminates volatile sulfur compounds (VSCs), the molecules responsible for halitosis.

No fluoride, SLS, parabens, or dyes — ideal for users with mouth ulcers, mucosal irritation, or chemical sensitivity.

Non-abrasive silica: safe for frequent brushing, with RDA low enough for enamel preservation.

Each application = one pea-sized dose delivers full bacterial coverage.

🧬 Formulated in gel form to preserve probiotic viability — viscosity is intentionally lower to avoid thickeners that would kill the living cultures.
Probiotic viability: live Bacillus coagulans (40 Billion CFU) vs. inert or degraded strains
SYMBIOS uses a spore-forming strain that activates only in saliva, ensuring high survivability through shelf-life and brushing.
By contrast, most probiotic pastes contain non-encapsulated strains (Lactobacillus, Bifidobacterium) that degrade from moisture, oxygen, or SLS.

Halitosis reduction: microbial cause vs. symptom masking
SYMBIOS inhibits Fusobacterium nucleatum and Prevotella intermedia—VSC-producing bacteria responsible for bad breath—yielding up to 60–65% VSC suppression in in vitro models.
Competing pastes use zinc, menthol, or chlorophyll to neutralize odors temporarily, without affecting bacterial load.

Caries prevention: bacterial competition vs. fluoride-only defense
B. coagulans reduces S. mutans by over 60% in saliva within 14 days. This directly lowers acid production and plaque formation—even without fluoride.
Most non-probiotic pastes depend solely on fluoride for demineralization resistance but lack bacterial load modulation.

Immune activation: mucosal immunity vs. no systemic effect
SYMBIOS’s strain upregulates T-cell cytokines (IFN-γ, TNF-α) by 400–700%, based on respiratory tract challenge models.
Other probiotic or herbal pastes have no measurable immunological impact beyond surface contact.

Microbial safety: does not disrupt beneficial flora
SYMBIOS reshapes the oral ecosystem by competitive exclusion, without killing commensals.
Traditional antibacterial pastes (triclosan, chlorhexidine) exert non-selective bactericidal effects, often disrupting oral microbiota and leading to fungal overgrowth.

Mucosal tolerance: non-irritating, alcohol- and SLS-free vs. detergent-based
The use of SL30 surfactant ensures foam without cytotoxicity. Studies show this reduces mucosal irritation risk by up to 80% vs. SLS.
Many “fresh breath” pastes still contain SLS or ethanol, both known triggers for ulcers and mucosal dryness.

Remineralization support: xylitol + salivary enhancement
SYMBIOS includes xylitol to inhibit S. mutans adhesion and stimulate saliva, which delivers natural calcium/phosphate ions.
Other probiotic formulations rarely support remineralization conditions, relying solely on the probiotic concept.

Formulation stability: viable for >18 months at room temp
Spore-encapsulated B. coagulans in SYMBIOS retains functional CFU counts for over 18 months, unlike freeze-dried or liquid cultures that lose activity rapidly post-opening.

💡 Few know: SYMBIOS’s probiotic strain (JYBC-016) was originally tested as a pediatric gut immunobiotic, but oral studies revealed it could colonize tooth surfaces, produce lactic acid-neutralizing enzymes, and inhibit 3 key periodontal pathogens simultaneously.

SYMBIOS “LIVING” TOOTHPASTE WITH PROBIOTICS AND PREBIOTICS

Composition & Biocompatibility

Freshness & Safety

Advantages over Other Probiotic Toothpastes