معجون أسنان سيمبيوس "ليفينج" مع البروبيوتيك والبريبايوتكس

• Xylitol + Menthol + Probiotic synergy eliminates volatile sulfur compounds (VSCs), the molecules responsible for halitosis.

• No fluoride, SLS, parabens, or dyes — ideal for users with mouth ulcers, mucosal irritation, or chemical sensitivity.

• Non-abrasive silica: safe for frequent brushing, with RDA low enough for enamel preservation.

• Each application = one pea-sized dose delivers full bacterial coverage.

🧬 Formulated in gel form to preserve probiotic viability — viscosity is intentionally lower to avoid thickeners that would kill the living cultures.

• Probiotic viability: live Bacillus coagulans (40 Billion CFU) vs. inert or degraded strains
  SYMBIOS uses a spore-forming strain that activates only in saliva, ensuring high survivability through shelf-life and brushing.
  By contrast, most probiotic pastes contain non-encapsulated strains (Lactobacillus, Bifidobacterium) that degrade from moisture, oxygen, or SLS.

• Halitosis reduction: microbial cause vs. symptom masking
  SYMBIOS inhibits Fusobacterium nucleatum and Prevotella intermedia—VSC-producing bacteria responsible for bad breath—yielding up to 60–65% VSC suppression in in vitro models.
  Competing pastes use zinc, menthol, or chlorophyll to neutralize odors temporarily, without affecting bacterial load.

• Caries prevention: bacterial competition vs. fluoride-only defense
  B. coagulans reduces S. mutans by over 60% in saliva within 14 days. This directly lowers acid production and plaque formation—even without fluoride.
  Most non-probiotic pastes depend solely on fluoride for demineralization resistance but lack bacterial load modulation.

• Immune activation: mucosal immunity vs. no systemic effect
  SYMBIOS’s strain upregulates T-cell cytokines (IFN-γ, TNF-α) by 400–700%, based on respiratory tract challenge models.
  Other probiotic or herbal pastes have no measurable immunological impact beyond surface contact.

• Microbial safety: does not disrupt beneficial flora
  SYMBIOS reshapes the oral ecosystem by competitive exclusion, without killing commensals.
  Traditional antibacterial pastes (triclosan, chlorhexidine) exert non-selective bactericidal effects, often disrupting oral microbiota and leading to fungal overgrowth.

• Mucosal tolerance: non-irritating, alcohol- and SLS-free vs. detergent-based
  The use of SL30 surfactant ensures foam without cytotoxicity. Studies show this reduces mucosal irritation risk by up to 80% vs. SLS.
  Many “fresh breath” pastes still contain SLS or ethanol, both known triggers for ulcers and mucosal dryness.

• Remineralization support: xylitol + salivary enhancement
  SYMBIOS includes xylitol to inhibit S. mutans adhesion and stimulate saliva, which delivers natural calcium/phosphate ions.
  Other probiotic formulations rarely support remineralization conditions, relying solely on the probiotic concept.

• Formulation stability: viable for >18 months at room temp
  Spore-encapsulated B. coagulans in SYMBIOS retains functional CFU counts for over 18 months, unlike freeze-dried or liquid cultures that lose activity rapidly post-opening.

💡 Few know: SYMBIOS’s probiotic strain (JYBC-016) was originally tested as a pediatric gut immunobiotic, but oral studies revealed it could colonize tooth surfaces, produce lactic acid-neutralizing enzymes, and inhibit 3 key periodontal pathogens simultaneously.